HPMC Capsules – Vegetarian Hypromellose (Pharma Grade 2910)
HPMC (hypromellose) capsules are a plant-based alternative to gelatin capsules, valued for a vegetarian and vegan profile, low moisture content and good stability – which is why they suit hygroscopic actives and probiotic or moisture-sensitive fills that would struggle in gelatin.
Vegetarian HPMC capsules
Our pharmaceutical-grade HPMC for capsules uses substitution type 2910 (with 2208 available as a related type), described by its pharmacopoeia substitution number rather than a marketing code.
Pharma-grade substitution types
The substitution type is what a formulator actually selects on: it sets the methoxyl and hydroxypropoxyl content, and with it the gel temperature and solubility behaviour of the shell.
Substitution profiles we document
Pharmacopoeia substitution types we document (ChP 2020 aligned): 2910: methoxyl 28.0-30.0%, hydroxypropoxyl 7.0-12.0%, gel 58-64 C; 2906: methoxyl 27.0-30.0%, hydroxypropoxyl 4.0-7.5%, gel 62-68 C; 2208: methoxyl 19.0-24.0%, hydroxypropoxyl 4.0-12.0%, gel 70-90 C. High-viscosity grades are documented to a K100M-class standard (75,000-140,000). These are pharmacopoeia substitution numbers, not marketing codes.
Quality standard and documents
We make it to a quality standard that follows the Chinese Pharmacopoeia (ChP 2020), with NMPA excipient registration F20240000184 and long-term stability data on file. Every viscosity comes in both NDJ and Brookfield, always with the test conditions – concentration, temperature, spindle and speed – so the number you check on arrival matches the one we shipped against. Certificates we hold are available for your review. We publish no ratings or testimonials for this product, because we hold no customer evaluation data and will not invent it. We make no international-pharmacopoeia claim here – what we can document is the ChP 2020 line above.
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HPMC product page
HPMC / hydroxypropyl methyl cellulose for construction and industry: water retention and rheology grades.
Open →Pharmacopoeia compliance
Pharmacopoeia compliance and audit support for excipient sourcing: ChP 2020 and NMPA on file, with change control and audit policy.
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Open →ChP 2020 + NMPA originals – the most complete pharma-grade evidence we hold. International pharmacopoeia not claimed. No invented ratings.
Frequently Asked Questions
Are HPMC capsules suitable for vegetarians and vegans?
Yes – they are plant-based, a common reason buyers move away from gelatin, and they carry low moisture, which helps with hygroscopic or moisture-sensitive fills.
What is substitution type 2910, and do you offer others?
2910 is a pharmacopoeia substitution designation (methoxyl 28.0-30.0%, hydroxypropoxyl 7.0-12.0%); we also work with 2208. We describe grades by these numbers rather than by a marketing code.
Which documents can you provide?
A ChP 2020-aligned quality standard, NMPA excipient registration F20240000184 and long-term stability data – originals on file. Ask and we send them with a sample.